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Santos FC host San Lorenzo de Almagro on Thursday, May 21 at 12:00 AM in a top-four clash that could have significant title implications. Both sides are separated by just 3 points in the Group D, making this one of the more consequential fixtures of the season.
Santos FC come into this fixture drawing too many games (3D in last 4). San Lorenzo de Almagro, meanwhile, arrive drawing too many games (3D in last 4) — actually the better-performing side in recent weeks.
Head-to-head records offer little separation — Santos FC and San Lorenzo de Almagro have split their 5 meetings almost evenly (2W–2D–1W). Their last encounter ended in a 1–1 draw. These two tend to produce goals — averaging 2.8 per game in recent meetings.
Verdict: This looks an evenly matched contest. Home advantage gives Santos FC a slight edge, but San Lorenzo de Almagro are capable of causing problems. A draw would be a fair result.

